00
Personal Information
Dor Mohammad Kordi Tamandani
Department : Department of Biology
Degree : Assistant Professor
Internal Phone : 2641
External Phone : +98 54 31132641
Fax : +98 54 33446565
Email : dor_kordi@yahoo.com
Google Scholar Profile :

Address : Department of Biology, Sistan and Baluchistan University,

01
Educations

General English, Physics, Chemistry, Biology, Mathematics

Name of University: S&B State Board of School Education
Degree: Bs.C

DVM

Name of University:  Ferdowsi University of Mashhad Iran
Degree: DVM

Biotechnology(Molecular genetics)

Name of University: Panjab university , Chandigarh- India (UGS fellowship)
Degree: Ph.D
02
Conferences

Promoter Methylation and Expression profile of the (p15INK4b ,p16INK4a CHD1 and MGMT) Genes in the Clinical Estimation of Oral Cavity Cancer

Authors:Dor Mohammad kordi Tamandani, ,Abdul karim moazeni, Mohammad Ayub Rigi Ladies ,Alnaze Birjandian
Conference: EPIGENETICS AND STEM CELLS CONFERENCE
Place: Copenhagen, Denmark

Authors:Kordi Tamandani DM
Conference: Asia2010, the global bio business forum
Place: Hyderabad, India

CYTOKINE GÈNES (IL-1, 1L-RA,IL-12,IFN- GAMMA)POLYMORPHISM AND CERVIX CANCER RISK

Authors:Kordi Tamandani DM, Moazeni K, Torkamanzahi A, Sharifi N, Sobti RC, Shekari M, Huria A
Conference: 8th congres of the European Socity of Gynecology
Place: Roma,Itlay

CPG island methylation of TMS1/ASC and CASP8 genes in cervical cancer

Authors:Kordi Tamandani DM, Sobti, RC, Shekari M
Conference: International symposium on Epigenetic Modifications of the Genome
Place: CCMB,India

Impact of IFN-Gamma on the risk of cevical cancer in North Indian population ,

Authors:Tamandani DMK,.Sobti RC, Shekari M
Conference: International Symposium on Genetics,Health and Disease
Place: Amritsar ,India.

Interaction of passive Smoking with Il-b genotype in the risk of cervical cancer in north Indian population

Authors:D. M. Kordi Tamandani, R. C. Sobti, M. Shekari, P. Kaur, S. Kaur , V.Suri,
Conference: international Symposium on Genomic Instability and Cancer
Place: Sringar, J&K – India

. DNA repair gene (NBS1GLU/185/GLN) polymorphism and

Authors:M. Shekari, R. C. Sobti, D.M. Kordi Tamandani, P.Kaur, S. Kaur , V. Suri,
Conference:  international Symposium on Genomic Instability and Cancer
Place: Sringar, J&K – India.

Association of proinflammatory cytokine gene polymorphism with susceptibility of cervical cancer

Authors:M. Kordi Tamandani, R.C.Sobti, M. Shekari
Conference: International Symposium on Health Informatics and Bioinformatics
Place: Antalya, Turkey
03
Journals

Promoter hypermethylation and expression profile of MGMT and CDH1 genes in oral cavity cancer.

Authors:Kordi-Tamandani DM, Moazeni-Roodi AK, Rigi-Ladiz MA, Hashemi M, Birjandian E, Torkamanzehi A
Journal:Arch Oral Biol. 2010 Jul 30. [Epub ahead of print]

Lack of association between paraoxonase-1 Q192R polymorphism and rheumatoid arthritis in southeast Iran.

Authors:Hashemi M, Moazeni-Roodi AK, Fazaeli A, Sandoughi M, Bardestani GR, Kordi-Tamandani DM, Ghavami S.
Journal:Genet Mol Res. 2010 Feb 23;9(1):333-9.

Analysis of methylation patterns and expression profiles of p14ARF gene in patients with oral squamous cell carcinoma.

Authors:Kordi-Tamandani DM, Moazeni-Roodi A, Rigi Ladez MA, Hashemi M, Birjandian E, Torkamanzehi A
Journal:Int J Biol Markers. 2010 Apr-Jun;25(2):99-103.

The L55M polymorphism of paraoxonase-1 is a risk factor for rheumatoid arthritis.

Authors:Hashemi M, Moazeni-Roodi AK, Fazaeli A, Sandoughi M, Taheri M, Bardestani GR, Zakeri Z, Kordi-Tamandani DM, Ghavami S
Journal:Genet Mol Res. 2010 Aug 31;9(3):1735-41.

Interleukin-12 genes polymorphism and cervical cancer risk

Authors:Kordi Tamandani DM, Sobti RC, Shekari M, et al
Journal:American Journal of Clinical

No association of TAP1 and TAP2 genes polymorphism with risk of cervical cancer in north Indian population

Authors:Kordi Tamandani DM , Sobti R C , M Shekari
Journal: J Assist Reprod Genet [Epub ahead of print]

Methylation Patterns of Rb1 and Casp-8 Promoters and Their Impact on Their Expression in Bladder Cancer

Authors:Malekzadeh K, Sobti RC, Nikbakht M, Shekari M, Hosseini SA, Tamandani DK, Singh SK
Journal:Cancer Invest 21:1. [Epub ahead of print]

Impact of methylenetetrahydrofolate reductase (MTHFR) codon (667) and methionine synthase (MS) codon (2756) on risk of cervical carcinogenesis in North Indian population

Authors:Sobti R C , M Shekari, Kordi Tamandani DM
Journal:Arch Gynecol Obstet 278(6):517-24

Association of Fas -670 gene polymorphism with risk of cervical cancer in north Indian population

Authors:.Kordi Tamandani DM, Sobti RC, Shekari M
Journal:Exp ncol 30(3):224-9

Expression and polimorphism of IFN-gamma gene in patients with cervical cancer

Authors:Tamandani DMK,.Sobti RC, Shekari M
Journal:Exp Oncol.30(3):224-9.

Effect of NBS1 Gene Polymorphism with the Risk of Cervix Carcinoma in North Indian Population

Authors:Sobti RC. Shekari M., Kordi Tamandani DM
Journal:Int J Biol Markers 23(3):133-9

Impact of IL- Ra on risk of cervical cancer

Authors:Kordi Tamandani DM, Sobti RC, Shekari M, Kaur S, Huria A
Journal:Arch Gynecol Obstet. Arch Gynecol Obstet 277(6):527-33

1beta gene polymorphism and cervical cancer risk

Authors:Sobti R C, Kordi Tamandani D M , M Shekari , P Kaur , KMalekzadeh , V
Journal:Int J Gynaecol Obstet.101(1):47-52

CPG island methylation of TMS1/ASC and CASP8 genes in cervical cancer

Authors:Kordi Tamandani DM, Sobti, RC, Shekari M
Journal:Eur J Med Res 13: 1-5

Association f genetic polymorphism of the DNA base excision repair gene (APE-1 Asp/148Glu) and HPV type (16/18) with the risk of cervix cancer in north Indian population

Authors:Shekari M, Sobti Ranbir C, Kordi Tamandani DM , M Keyanoosh, PKaur, V
Journal:Cancer Biomark 4(2):63-71

Association of IL-18 gene promoter polymorphism on the risk of cervix carcinoma in North Indian population

Authors:Shekari M, Sobti R C, Kordi Tamandani DM
Journal:Oncol Res 17(4):159-66
04
Research Interests

1. Eukaryotic gene expression

2. Molecular biology of infectious diseases

3. Cancer epigenetic

4. Molecular genetics of Cancer

5. Gene expression and regulation in mammalian systems

05
Research Projects

1.Analysis of DNA Hypermethylation of promoter region of five candiate genes in saliva as bimarker for early dignosis of oral cavity cxancer

Researcher : Prof. Tourkamanzahi,DM Kordi Tamandani,Dr R.Ladize, , Dr. Hashemi
Start Date : 2008.9.1
End Date :
Place : USB

2.Epigenetic study of same candiate genes on Tissue embedded samples of patients with oral cavity cancer

Researcher : Prof. Tourkamanzahi,DM Kordi Tamandani,Dr R.Ladize, , Dr. Hashemi
Start Date : 2008.9.1
End Date : 2009.6.1
Place : USB

3.Identification of Biomarkers for Non-alcoholic fatty liver disease (NAFLD)

Researcher : DM Kordi Tamandani, Prof. Tourkamanzahi,Dr. Hashemi
Start Date : 2009.3
End Date :
Place : USB

4.Identification of Biomarkers for Metabolic syndrome

Researcher : DM Kordi Tamandani,Prof. Tourkamanzahi, , Dr. Hashemi
Start Date : 2009.5
End Date :
Place : USB
06
Skills

• Tissue Culture: ex vivo studies on epithelial cell lines.

• Animal Work: Handling of experimental animals (mice, rats, guinea pigs and rabbits); Drug administration (through oral, subcutaneous, intraperitoneal & intravenous routes); Blood collection and disectioning; Collection and processing of tissues, separating sub cellular fractions by differential and density gradient centrifugation; Preparation of nuclear extracts

• Enzymatic and Protein Chemistry Work: Extraction and purification of enzymes from animal tissues; Determination of enzymatic activities, study of enzyme kinetics and characterization by SDS-PAGE; Protein expression studies by western blotting and immunocytochemistry; Isolation and purification of proteins by Gel filtration, Ion-exchange chromatography, Affinity chromatography and HPLC.

• Molecular and Cell Biology Techniques: DNA/RNA isolation and purification from bacteria, mammalian blood and tissue systems; Agarose and polyacrylamide gel electrophoresis; Gene expression profiles by northern blotting & RT-PCR analysis; Membrane transport studies; Role of different signaling pathways like cAMP, PKC & PKA in viable cell cultures in membrane transport; FACS analysis; Blast search for designing primers and probes; Genomic and gene specific methylation studies including methylation specific PCR and bisulphite studies.

• Genetic and Epigenetics Studies: Polymorphism and Mutation in population based studies by RFLP, RAPD, SSCP; DNA Methylation and inheritance

• Microscopic and Pathological Studies: Transmission Electron Microscopic (TEM) studies of the tissue membranes under high and low power for structural functional interrelationships; Immunohistochemistry for the localization and derangement of the receptor expression; Histopathological studies for changes in the tissue architecture.

• Immunological Techniques: Raising the antisera against the synthetic and purified peptides in rabbits and their purification; Quantitative & qualitative characterization of antigen-antibody reactions by ELISA, western blotting, double immuno-diffusion and dot blotting.

• Biochemical Techniques: DNA, RNA and protein estimation using colorimetric, fluorometric and UV-spectrophotometeric studies; Alcohol and folate estimation from blood, serum and RBC using radio immune assay and microbiological assay using lactobacillus casei; HPLC for quantitation of S-adenosyl methionine and S-adenosyl homocysteine from blood and tissues; Use of scintillation counters.

• Statistical analysis: Statistical analysis of raw data; Student’s t-test, ANOVA and post ANOVA tests and other statistical calculations.

• Statistical analysis: Statistical analysis of raw data; Student’s t-test, ANOVA and post ANOVA tests and other statistical calculations.

07
Works

1.13th ADNAT CONVENTION

Mechanisms and Implications & A Hands-on Training Course on Basic


2.Indo-Us flow cytmetry workshop

Proliferation, Apoptosis and Signal Transduction


3. Indo-Us Symposium on stem cell identification and characterization:

Roll of Molecular Markers


4. 9 th Chandigrah Symposium on new biology:

post genomic era: Emergence


5.National workshop

Bioinformatics Resources on miRNA and siRNA


6. National workshop

Techniques in Molecular Biology and Human


7. European Molecular Biology Organization (EMBO) workshop

“Developmental Mechanism of disease Models


8. stem cell

Futuristic therapy in Making


9.Indo-US workshop

mitochondrial Research and Medicine


10.Indo-US CME &workshop

Molecular Techniques for the Diagnosis of Parasitic


11. One monthworkshop in field of parental diagnosis, triple screening, B-THAL,A-THAL, Thrombosis, Hemophilia, Fragile-x at the department of Hematology

PGIMER Chandigarh 160 012, India


12.Six month training course

Immunogenetics, Molecular Biology, Molecular genetics, Cancer gene therapy


13.Indo-Us Seminar-Cum- Demonstrative workshop

Anomal cell culture,DNA Fingerpriting & cell Marker Identification


14.Winter Workshop

Molecular Diagnosis of Genetic Disorders


15.International workshop &conference

Medical and community Genetics


16.International socity for Heart Research